
Can Collagenase Dissolve Ellansé (PCL)? Contested Evidence
People are starting to say collagenase can dissolve Ellansé nodules. There is a 2025 study that claims this, but it has only 3 patients, was publicly questioned by peers as soon as it appeared, and rests on an unresolved contradiction: collagenase breaks down collagen, while Ellansé's PCL is a polyester. This article lays out the evidence honestly and explains why ultrasound-guided physical extraction remains the more predictable route for now.



















































