Hyaluronic Acid Forum: Patient Questions & Doctor Answers

Real questions from patients dealing with Hyaluronic Acid, answered in the thread by Dr. Ta-Ju Liu. Read what others asked, or post your own question.

5 threads

Full explanation from Dr. Liu

People Also Ask

Why is the lump still there even after trying hyaluronidase injections multiple times?

When a hyaluronic acid lump does not dissolve after hyaluronidase, several factors may be involved. The filler may be encapsulated by fibrous tissue, which shields it from the enzyme. Alternatively, cross-linked product characteristics or filler placement deep within muscle layers can impede complete breakdown. Chronic inflammation over time can also form granulomatous tissue rather than pure gel. Ultrasound-guided evaluation can help assess whether residual material or fibrous capsule tissue remains. If you are worried, consult a filler-revision specialist.

Can ultrasound really tell if a bump is leftover hyaluronic acid filler or something else?

Yes, high-resolution ultrasound is a valuable tool for assessing facial lumps following cosmetic injections. It visualizes the exact anatomical depth, distinguishing whether a mass resides in subcutaneous fat or muscle planes. Ultrasound also differentiates between cystic hyaluronic acid gel pockets, autologous fat, fibrous tissue, and surrounding edema. This objective imaging assists in planning targeted aspiration or enzymatic correction rather than blind intervention. If you are worried, consult a filler-revision specialist.

Why am I having persistent headaches and temple pain after temple filler injections?

Persistent pain radiating from the temples to the back of the head after filler injections may stem from mechanical nerve compression, deep tissue pressure, or vascular compromise. Even without visible surface redness or swelling, filler placed in deep fascial spaces can irritate adjacent sensory nerves, causing severe, refractory headaches. Repeating hyaluronidase without targeted imaging may leave the offending pressure unresolved. Prompt medical evaluation is essential to rule out complications. If you are worried, consult a filler-revision specialist.

What should I do if an under-eye filler lump appears years later and looks like a caterpillar when I smile?

Under-eye protrusions that become prominent when smiling often occur when filler is injected too superficially or shifts into the superficial orbicularis oculi muscle layer. Delayed inflammatory reactions or water absorption can also create long-standing unevenness resembling ribbons or lumps. When hyaluronidase is delayed or fails due to encapsulation, specialized micro-aspiration, ultrasound-guided dissolution, or minimal revision approaches may be explored after proper diagnostic imaging. If you are worried, consult a filler-revision specialist.

Can an area treated with both fat grafting and hyaluronic acid still be fixed if lumps remain?

Lumps in areas treated with both autologous fat and hyaluronic acid can be challenging, but they can still be systematically addressed. Because fat necrosis and persistent filler respond to entirely different interventions, clarifying the composition via ultrasound is essential. While hyaluronic acid can be dissolved with hyaluronidase, fat nodules or fibrous scar tissue may require micro-liposuction, surgical trimming, or specialized aspiration techniques to smooth contour irregularities. If you are worried, consult a filler-revision specialist.

Hyaluronic Acid (HA) Filler

Hello. I have had Hyaluronic Acid (HA) fillers injected and dissolved in my nasolabial folds multiple times. About four years ago, I also used a collagen booster called Juvelook, which caused no issue...

Anonymous · 4 replies · Answered
Headaches caused by Hyaluronic Acid in the temples

Dear Dr. Liu, I had 1cc of Juvederm injected into my temples in Korea three weeks ago. Shortly after, I began experiencing pain radiating from my temples to the back of my head. I have already had tw...

Sophia · 1 replies · Answered
Autologous Fat Nodules and Residual Hyaluronic Acid

Hello Dr. Liu, I have already booked an appointment for July, and I'd like to ask whether my condition is suitable for treatment. Thank you. Many years ago I had a failed fat grafting under my eyes, ...

海膽貓 · 1 replies · Answered
Tear Trough Lumps/Nodules

Hi everyone, I'd like to ask the experts here, or anyone who has had a similar experience... I had Princess hyaluronic acid filler injected into my tear troughs at a clinic, and now there are obvious...

77 · 3 replies